Document Detail

Mouse lambda-chain sequences.
MedLine Citation:
PMID:  4516208     Owner:  NLM     Status:  MEDLINE    
Amino-acid sequences of the variable regions of three lambda chains produced by plasmacytomas of BALB/c mice are compared. Two are almost certainly identical and one differs from these by three amino acids. These findings extend our earlier conclusion on the relative uniformity of sequences in this type of immunoglobulin light chain. With amino-acid sequence data on two additional lambda chains, eight mouse lambda chains studied to date are indistinguishable and four probably differ from these by one, two, or three amino acids.
I M Cesari; M Weigert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  70     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1973 Jul 
Date Detail:
Created Date:  1973-10-09     Completed Date:  1973-10-09     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2112-6     Citation Subset:  IM    
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MeSH Terms
Amino Acid Sequence
Immunoglobulin A / analysis
Immunoglobulin Fragments / analysis*,  isolation & purification
Mice, Inbred BALB C
Myeloma Proteins / analysis
Neoplasms, Experimental / metabolism
Peptides / analysis
Plasmacytoma / metabolism*
Reg. No./Substance:
0/Immunoglobulin A; 0/Immunoglobulin Fragments; 0/Myeloma Proteins; 0/Peptides; EC; EC; EC

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