Document Detail

Motor performance and disability in Dutch children with haemophilia: a comparison with their healthy peers.
MedLine Citation:
PMID:  11380634     Owner:  NLM     Status:  MEDLINE    
We investigated whether haemophilic children who are on prophylactic therapy differ from their healthy peers in terms of motor performance and disability. Thirty-nine children, aged 4-12 years, with moderate (eight) and severe (31) haemophilia were included. Patients with severe haemophilia received primary prophylactic therapy that was individually tailored. The number of target joints, amount of swelling, range of motion, muscular strength and pain were measured, as well as motor skills and disability. The scores were compared to the normal population. No patients had target joints. Normal range of motion in all joints was seen in 97% (38/39) of the patients. Strength of elbow, knee, and ankle muscles were within the normal ranges. Ninety-five percent (37/39) of the patients had normal motor performance. Although 90% of our patients (35/39) had no disabilities in activities of daily living (ADL), 79% (31/39) of them reported that the disease impacted on their lives. Seventy-two percent (28/39) of the patients had pain, and in 21% (6/28) of them this was mainly caused by injections. Restrictions in sports or gymnastics were seen in 56% (22/39) of the patients. Those who indicated that they experienced pain and those who indicated restrictions in sports had a higher chance of experiencing disease impact compared to those who did not have these limitations. There were no significant differences between patients with moderate and severe haemophilia. In general, Dutch children with moderate or severe haemophilia are comparable with their healthy peers with regard to motor performance and ADL. However, a majority of the patients perceive an impact of their disease associated with pain and restrictions in sports.
M A Schoenmakers; V A Gulmans; P J Helders; H M van den Berg
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Haemophilia : the official journal of the World Federation of Hemophilia     Volume:  7     ISSN:  1351-8216     ISO Abbreviation:  Haemophilia     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-30     Completed Date:  2001-12-04     Revised Date:  2009-10-21    
Medline Journal Info:
Nlm Unique ID:  9442916     Medline TA:  Haemophilia     Country:  England    
Other Details:
Languages:  eng     Pagination:  293-8     Citation Subset:  IM    
Department of Paediatric Physiotherapy, Wilhelmina Children's Hospital, Utrecht, The Netherlands.
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MeSH Terms
Ankle Joint / physiopathology
Child, Preschool
Cross-Sectional Studies
Disability Evaluation*
Elbow Joint / physiopathology
Gymnastics / physiology
Hemophilia A / physiopathology*
Hemophilia B / physiopathology
Knee Joint / physiopathology
Muscle Weakness / etiology,  physiopathology
Musculoskeletal Physiological Phenomena*
Psychomotor Performance*
Quality of Life
Range of Motion, Articular
Severity of Illness Index

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