Document Detail


Motor neuron disease in 2012: Novel causal genes and disease modifiers.
MedLine Citation:
PMID:  23318296     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In 2012, researchers published extensively on the genetic and clinicopathological characterization of patients with the newly discovered C9ORF72 repeat expansions, which cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Novel ALS-linked genes and genetic modifiers were identified through screening in animal models and patients.
Authors:
Rosa Rademakers; Marka van Blitterswijk
Related Documents :
24450926 - Neuropathologic assessment of dementia markers in identical and fraternal twins.
16523516 - The arx mutations: a frequent cause of x-linked mental retardation.
21072176 - A non-coding rna within the rasgrf1 locus in mouse is imprinted and regulated by its ho...
23759146 - Novel progranulin variants do not disrupt progranulin secretion and cleavage.
25364816 - A genome-wide association study for diabetic retinopathy in a japanese population: pote...
14555306 - Identification of two novel mutations in the 5'-untranslated region of h-ferritin using...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-15
Journal Detail:
Title:  Nature reviews. Neurology     Volume:  -     ISSN:  1759-4766     ISO Abbreviation:  Nat Rev Neurol     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101500072     Medline TA:  Nat Rev Neurol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Chemical biology-based approaches on fluorescent labeling of proteins in live cells.
Next Document:  Reduction in swimming performance in juvenile rainbow trout (Oncorhynchus mykiss) following subletha...