Document Detail

Motor function improvement following intrathecal baclofen pump placement in a patient with locked-in syndrome.
MedLine Citation:
PMID:  11953549     Owner:  NLM     Status:  MEDLINE    
We describe a patient with locked-in syndrome who had minimal volitional motor function and severe spasticity in all four extremities. The patient showed a significant improvement in volitional motor function following intrathecal baclofen pump therapy to control spasticity. This case study suggests that intrathecal baclofen pump therapy might improve motor function in select patients with locked-in syndrome.
Kevin Cairns; Joel Stein
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of physical medicine & rehabilitation / Association of Academic Physiatrists     Volume:  81     ISSN:  0894-9115     ISO Abbreviation:  Am J Phys Med Rehabil     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-15     Completed Date:  2002-05-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8803677     Medline TA:  Am J Phys Med Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  307-9     Citation Subset:  AIM; IM    
Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital Network, Boston, Massachusetts 02114-1198, USA.
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MeSH Terms
Baclofen / therapeutic use*
Brain Stem Infarctions / complications
Infusion Pumps, Implantable*
Muscle Relaxants, Central / therapeutic use*
Muscle Spasticity / drug therapy*
Postoperative Complications
Quadriplegia / etiology,  rehabilitation*
Reg. No./Substance:
0/Muscle Relaxants, Central; 1134-47-0/Baclofen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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