Document Detail

Motor assessment in patients with Duchenne muscular dystrophy.
MedLine Citation:
PMID:  22699538     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: Evaluate muscle force and motor function in patients with Duchenne muscular dystrophy (DMD) in a period of six months.
METHOD: Twenty children and adolescents with diagnosis of DMD were evaluated trough: measurement of the strength of the flexors and extensors of the shoulder, elbow, wrist, knee and ankle through the Medical Research Council (MRC), and application of the Motor Function Measure (MFM). The patients were evaluated twice within a six-month interval.
RESULTS: Loss of muscle strength was identified in the MRC score for upper proximal members (t=-2.17, p=0.04). In the MFM, it was noted significant loss in the dimension 1 (t=-3.06, p=0.006). Moderate and strong correlations were found between the scores for muscular strength and the MFM dimensions.
CONCLUSION: The MFM scale was a useful instrument in the follow up of patients with DMD. Moreover, it is a more comprehensive scale to assess patients and very good for conducting trials to evaluate treatment.
Gabriela Palhares Campolina Diniz; Laura Maria de Lima Belizário Facury Lasmar; Juliana Gurgel Giannetti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  70     ISSN:  1678-4227     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  416-21     Citation Subset:  IM    
Hospital das Clínicas, Universidade Federal de Minas Gerais.
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