Document Detail

Motor performance improved by exercises in cerebral ischemic rats.
MedLine Citation:
PMID:  22364489     Owner:  NLM     Status:  MEDLINE    
Physical exercise may induce neuroprotective effects against brain damage after stroke. The authors aimed to investigate the effects of various exercises on motor function, striatal angiogenesis, and infarct volume in cerebral ischemic rats. Adult male Sprague Dawley rats were subjected to middle cerebral artery occlusion and randomly assigned to 1 of the 4 groups: Rota-rod training, lower speed treadmill training, higher speed treadmill training, or no exercise control. Motor function, striatal angiogenesis, and infarct volume were evaluated before or after motor training. After training, motor function and striatal angiogenesis changed significantly in Rota-rod and higher speed treadmill training groups as compared with the control group. Improvement in motor function significantly correlated with striatal angiogenesis after motor training. Infarct volumes were significantly decreased in lower and higher speed treadmill training groups. The results indicated that both motor training procedures can be used as effective training programs in stroke rehabilitation.
Yea-Ru Yang; Heng-Chih Chang; Paulus S Wang; Ray-Yau Wang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-02-24
Journal Detail:
Title:  Journal of motor behavior     Volume:  44     ISSN:  1940-1027     ISO Abbreviation:  J Mot Behav     Publication Date:  2012  
Date Detail:
Created Date:  2012-03-19     Completed Date:  2012-07-17     Revised Date:  2014-03-17    
Medline Journal Info:
Nlm Unique ID:  0236512     Medline TA:  J Mot Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  97-103     Citation Subset:  IM    
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MeSH Terms
Brain / pathology
Brain Ischemia / pathology,  rehabilitation*
Corpus Striatum / blood supply*,  pathology
Disease Models, Animal
Exercise Therapy / methods*
Infarction, Middle Cerebral Artery / pathology,  rehabilitation*
Neovascularization, Physiologic / physiology
Physical Conditioning, Animal / methods,  physiology*
Rats, Sprague-Dawley

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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