| Motion-sensitized driven equilibrium for blood-suppressed T2* mapping. | |
| | |
MedLine Citation:
|
PMID: 21769964 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE: To combine a motion-sensitized driven equilibrium (MSDE) preparation with a multi-echo spoiled gradient-echo sequence (SPGR) to suppress the blood signal intensity in T2* mapping of carotid plaques and liver. MATERIALS AND METHODS: The analytical solution of the Bloch equations for the multi-echo SPGR sequence, with and without the MSDE preparation, was calculated to optimize sequence parameters. The sequence was implemented at 3 Tesla and T2* maps of carotid plaques and liver were first optimized for blood suppression, and then acquired from five healthy livers and six subjects with ultrasound-identified carotid plaques. RESULTS: Simulations and experimental data showed that the flip angle that gives maximal signal (Ernst angle) in the MSDE-SPGR was greatly increased from that of pure SPGR. Robust blood suppression was obtained in the T2* maps of carotid plaques and liver, requiring suppression at a field of speed (FOS) of 30 cm/s in both the carotids and liver. CONCLUSION: MSDE provides a means to suppress the blood signal intensity in SPGR sequences. Tissue T2* maps can be obtained without the confounding effects originating from blood vessels. J. Magn. Reson. Imaging 2011;. © 2011 Wiley-Liss, Inc. |
| | |
Authors:
|
Rexford D Newbould; David R J Owen; Joseph Shalhoub; Andrew P Brown; Giulio Gambarota |
Related Documents
:
|
18848564 - Rapid loss of dendritic cell and monocyte responses to tlr ligands following venipuncture. 15278214 - Analysis of the henze precipitate from the blood cells of the ascidian phallusia mammil... 16867784 - Contribution to the methodology of optimization and in-process control of some physical... 11571894 - Rethinking blood shield statutes in view of the hepatitis c pandemic and other emerging... 7557614 - A survey of blood transfusion practices of gynecologic oncologists. 21382044 - Effect of applied muscle tension on cerebral oxygenation in female blood donors. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-18 |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: - ISSN: 1522-2586 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-7-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
|
GSK Clinical Imaging Centre, Hammersmith Hospital, London, United Kingdom. rexford.newbould@gmail.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Three-dimensional flow-independent balanced steady-state free precession vessel wall MRI of the popl...
Next Document: Three-dimensional plus time biventricular strain from tagged MR images by phase-unwrapped harmonic p...