Document Detail


Motion-sensitive cortex and motion semantics in American Sign Language.
MedLine Citation:
PMID:  22750056     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous research indicates that motion-sensitive brain regions are engaged when comprehending motion semantics expressed by words or sentences. Using fMRI, we investigated whether such neural modulation can occur when the linguistic signal itself is visually dynamic and motion semantics is expressed by movements of the hands. Deaf and hearing users of American Sign Language (ASL) were presented with signed sentences that conveyed motion semantics ("The deer walked along the hillside.") or were static, conveying little or no motion ("The deer slept along the hillside."); sentences were matched for the amount of visual motion. Motion-sensitive visual areas (MT+) were localized individually in each participant. As a control, the Fusiform Face Area (FFA) was also localized for the deaf participants. The whole-brain analysis revealed static (locative) sentences engaged regions in left parietal cortex more than motion sentences, replicating previous results implicating these regions in comprehending spatial language for sign languages. Greater activation was observed in the functionally defined MT+ ROI for motion than static sentences for both deaf and hearing signers. No modulation of neural activity by sentence type was observed in the FFA. Deafness did not affect modulation of MT+ by motion semantics, but hearing signers exhibited stronger neural activity in MT+ for both sentence types, perhaps due to differences in exposure and/or use of ASL. We conclude that top down modulation of motion-sensitive cortex by linguistic semantics is not disrupted by the visual motion that is present in sign language sentences.
Authors:
Stephen McCullough; Ayse Pinar Saygin; Franco Korpics; Karen Emmorey
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-06-27
Journal Detail:
Title:  NeuroImage     Volume:  63     ISSN:  1095-9572     ISO Abbreviation:  Neuroimage     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-08-28     Completed Date:  2013-01-29     Revised Date:  2013-10-17    
Medline Journal Info:
Nlm Unique ID:  9215515     Medline TA:  Neuroimage     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Laboratory for Language and Cognitive Neuroscience, San Diego State University, San Diego, CA, USA. mccullough@projects.sdsu.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Deafness / physiopathology*,  rehabilitation
Evoked Potentials, Visual*
Female
Humans
Magnetic Resonance Imaging / methods
Male
Motion
Motion Perception*
Semantics*
Sign Language*
Temporal Lobe / physiopathology*
United States
Grant Support
ID/Acronym/Agency:
R01 DC010997/DC/NIDCD NIH HHS; R01 DC010997/DC/NIDCD NIH HHS
Comments/Corrections

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