Document Detail

Motion analysis of single-level cervical total disc arthroplasty: a meta-analysis.
MedLine Citation:
PMID:  22615154     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: The purpose of this review was to investigate whether cervical total disc arthroplasty (CTDA) preserves motion of the treated level and what its effect is on adjacent segments.
METHODS: Relevant published reports were collected from PubMed, Medline and Cochrane library. The original studies were considered eligible only if the range of motion (ROM) of the index or adjacent level had been investigated. A meta-analysis was then performed on the collected data. Statistical heterogeneity across the various trials was tested using Cochran's Q statistic and I (2) ; in the case of heterogeneity, a random effect model was used.
RESULTS: The weighted mean differences (WMDs) of the index level were 0.34 (95% confidence interval [CI], -0.53∼1.21, P = 0.440) and 0.23 (95% CI, -1.92∼2.38, P = 0.834) in all included studies and randomized control trials (RCTs), respectively. The WMDs of the cranial adjacent levels, caudal adjacent levels and whole cervical spines were 1.01 (95% CI, 0.55∼1.47, P = 0.000), 1.10 (95% CI, 0.61∼1.59, P = 0.000) and 3.40 (95% CI, -6.02∼12.82, P = 0.479), respectively.
CONCLUSION: These findings suggest that the protective effect against adjacent segment degeneration provided by cervical arthroplasty might not be as good as has been believed. Long-term supporting evidence is still needed.
Jian Chen; Shun-Wu Fan; Xin-Wei Wang; Wen Yuan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Orthopaedic surgery     Volume:  4     ISSN:  1757-7861     ISO Abbreviation:  Orthop Surg     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101501666     Medline TA:  Orthop Surg     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  94-100     Citation Subset:  IM    
Copyright Information:
© 2012 Tianjin Hospital and Blackwell Publishing Asia Pty Ltd.
Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Medical College of Zhejiang University and Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou.
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