Document Detail


Motion VEPs, stereopsis, and bifoveal fusion in children with strabismus.
MedLine Citation:
PMID:  10670470     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The link between nasal-temporal motion asymmetries and anomalous binocular sensory function in infantile esotropia (ET) has led to the idea that visual evoked potential responses to horizontal motion (mVE) is an alternative measure of sensory binocularity to stereopsis. A second hypothesis is that the mVEP response is a marker for bifoveal fusion. The purpose of this study was to directly evaluate these two hypotheses by examining the correspondence between the mVEP response and both stereoacuity and bifoveal fusion in a cohort of strabismic patients with variable binocular sensory function. METHODS: Motion VEPs, random dot stereopsis, and bifoveal fusion were measured in 94 children: 20 with infantile ET, 16 with infantile accommodative ET, 22 with late-onset accommodative ET, 10 with intermittent infantile strabismus, and 26 normal control participants. RESULTS: Patients with infantile ET and infantile accommodative ET had high concordance between mVEP responses and stereoacuity and mVEP responses and bifoveal fusion. Asymmetric mVEP responses were highly concordant with both no measurable stereopsis and an absence of fusional vergence. Patients with late-onset accommodative ET and intermittent infantile strabismus revealed discordance between the mVEP response and stereoacuity and high concordance between the mVEP response and bifoveal fusion. Asymmetric mVEP responses were highly concordant with the absence of bifoveal fusion and the minimum-size prism to elicit fusional vergence. CONCLUSIONS: The qualitative and quantitative relationship between the mVEP response and fusional vergence suggests that the mVEP response is an objective measure of bifoveal fusion. The availability of such a test will facilitate studies of normal development of bifoveal fusion and development of monofixation syndrome in strabismus.
Authors:
S L Fawcett; E E Birch
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  41     ISSN:  0146-0404     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-02-15     Completed Date:  2000-02-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  411-6     Citation Subset:  IM    
Affiliation:
Retina Foundation of the Southwest, Dallas, Texas 75231, USA. fawcett@metronet.com
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MeSH Terms
Descriptor/Qualifier:
Accommodation, Ocular
Child
Child, Preschool
Depth Perception / physiology*
Diagnostic Techniques, Ophthalmological
Esotropia / physiopathology*
Evoked Potentials, Visual / physiology*
Female
Fovea Centralis / physiology*
Humans
Infant
Male
Motion Perception / physiology*
Vision, Binocular / physiology*
Visual Acuity
Grant Support
ID/Acronym/Agency:
EY05236/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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