| Motility, expression of surface antigen, and X and Y human sperm separation in in vitro fertilization medium. | |
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MedLine Citation:
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PMID: 6542031 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The influence of surrounding medium on human sperm swimming behavior has been characterized. In modified Ham's F-10 serum-supplemented in vitro fertilization medium, the straight-track swimming pattern of sperm in semen changed rapidly into circular tracks, and a new surface antigen was detected soon after this change. The circular tracks alternated between clockwise and counterclockwise directional movements. Addition of 17 beta-estradiol in a concentration range found in follicular fluid increased the frequency of clockwise movement twofold, suggesting that a steep concentration gradient created by an aduterine flow during ovulation, is likely to direct sperm migration up the gradient in the ipsilateral oviduct. Separation of X and Y sperm raised the possibility that a female carrier of an X-linked disease might choose to have a daughter, instead of taking the chance of having an affected son. |
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Authors:
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S Sarkar |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Fertility and sterility Volume: 42 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1984 Dec |
Date Detail:
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Created Date: 1985-01-17 Completed Date: 1985-01-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 899-905 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Monoclonal
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immunology Antigens, Surface / analysis* Cell Fractionation Estradiol / pharmacology Female Fertilization in Vitro* Heterozygote Detection Humans Linkage (Genetics) Male Sex Chromosome Aberrations / genetics, prevention & control Sperm Motility* Spermatozoa / classification*, immunology X Chromosome Y Chromosome |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antigens, Surface; 50-28-2/Estradiol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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