Document Detail

Motility changes associated with large bowel obstruction and its surgical relief.
MedLine Citation:
PMID:  6548346     Owner:  NLM     Status:  MEDLINE    
Strain gauges and electrodes to detect intestinal motility were attached to the terminal ileum, right and left sides of the colon in Rhesus monkeys. Baseline recordings were made. An obstruction device was applied to the left colon at a laparotomy. Compromise of the bowel lumen leading to total obstruction occurred at 13 +/- 2 days. As obstruction progressed, contractions decreased in the terminal ileum and right colon but increased in the left colon proximal to the obstruction. Distention wave forms increased in the colon proximal to the obstruction. Visible intestinal movement, borborygmi and signs suggesting colic were accompanied by a motility phenomenon, simultaneous mass actions, not seen in normal unobstructed bowel. The obstructed segment was resected and an anastomosis made. The motility recordings revealed that postoperative ileus persisted for less than 48 hours and motility returned to normal significantly earlier than after a control laparotomy.
I Fraser
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of the Royal College of Surgeons of England     Volume:  66     ISSN:  0035-8843     ISO Abbreviation:  Ann R Coll Surg Engl     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-11-05     Completed Date:  1984-11-05     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7506860     Medline TA:  Ann R Coll Surg Engl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  321-6     Citation Subset:  IM    
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MeSH Terms
Colon / physiopathology
Colon, Sigmoid / physiopathology
Colonic Diseases / physiopathology*,  surgery
Disease Models, Animal
Gastrointestinal Motility*
Ileum / physiopathology
Intestinal Obstruction / physiopathology*,  surgery
Intestinal Pseudo-Obstruction / physiopathology
Macaca mulatta
Postoperative Complications
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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