| Mothers' reactions to prenatal diagnostic procedures and dexamethasone treatment of congenital adrenal hyperplasia. | |
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MedLine Citation:
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PMID: 8892164 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A retrospective survey of mothers' attitudes toward and experiences of chorionic villus sampling, amniocentesis and dexamethasone (DEX) treatment was conducted in 38 women who underwent a prenatal diagnostic procedure for congenital adrenal hyperplasia because of a previously affected child (n = 37) or because the mother herself was affected (n = 1). Both diagnostic procedures were well tolerated and almost every woman said that the anxiety or discomfort associated with the procedure was far outweighed by the value of knowing whether or not her fetus was affected. The earlier diagnostic information provided by chorionic villus sampling was highly valued. Maternal side-effects of DEX were common (75%) and more than one-third of the women rated one or more side-effects as "severe' (weight gain, fatigue, stomach pain, irritability, facial hair growth). Many women expressed anxiety about possible short- and long-term side-effects of DEX on their unborn children and themselves but all said they would undergo DEX treatment again to prevent virilization. |
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Authors:
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P D Trautman; H F Meyer-Bahlburg; J Postelnek; M I New |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of psychosomatic obstetrics and gynaecology Volume: 17 ISSN: 0167-482X ISO Abbreviation: J Psychosom Obstet Gynaecol Publication Date: 1996 Sep |
Date Detail:
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Created Date: 1997-01-30 Completed Date: 1997-01-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8308648 Medline TA: J Psychosom Obstet Gynaecol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 175-81 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Cornell Medical College, New York, NY, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Hyperplasia, Congenital
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diagnosis*,
drug therapy* Adult Amniocentesis / psychology Anxiety / psychology Attitude to Health* Chorionic Villi Sampling / psychology Dexamethasone / therapeutic use* Female Glucocorticoids / therapeutic use* Humans Mothers / psychology* Prenatal Diagnosis / psychology* Questionnaires Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 50-02-2/Dexamethasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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