Document Detail


Mother's environmental tobacco smoke exposure during pregnancy and externalizing behavior problems in children.
MedLine Citation:
PMID:  23178460     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: While the impact of active maternal smoking during pregnancy on child health has been well investigated, the association between maternal passive smoking, or environmental tobacco smoke (ETS), or second-hand smoke, and behavioral development of offspring is less clear. This study examines the association between maternal ETS exposure during pregnancy and child behavior problems.
METHODS: Cross-sectional data of 646 mother-child pairs from the Jintan China Cohort Study were used in the analyses. Mother's exposure to tobacco smoking at home, the workplace, and other places during pregnancy (for the determination of maternal ETS exposure) and children's behaviors (via Child Behavior Checklist) were assessed when the children were 5-6 years old. Logistic regression models were constructed to examine associations between maternal exposure to ETS during pregnancy and internalizing and externalizing behavior problems, adjusting for potential cofounders including child sex and parental characteristics.
RESULTS: 37% of mothers reported ETS during pregnancy. Children of mothers exposed to ETS during pregnancy had higher scores for externalizing and total behavior problems, with 25% of children whose mothers were exposed to ETS compared to 16% of children of unexposed mothers. After adjusting for potential confounders, ETS exposure was associated with a higher risk of externalizing behavior problems in offspring of exposed mothers (OR=2.08, 95% confidence interval [CI] 1.27-3.43). Analysis after multiple imputations and sensitivity analysis further verified the association, but no dose-response relationship was found. ETS exposure, however, was not associated with internalizing or total behavior problems.
CONCLUSION: This study suggests that maternal ETS exposure during pregnancy may impact child behavioral development, particularly externalizing behaviors.
Authors:
Jianghong Liu; Patrick W L Leung; Linda McCauley; Yuexian Ai; Jennifer Pinto-Martin
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2012-11-23
Journal Detail:
Title:  Neurotoxicology     Volume:  34     ISSN:  1872-9711     ISO Abbreviation:  Neurotoxicology     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-01-28     Completed Date:  2013-07-09     Revised Date:  2014-01-09    
Medline Journal Info:
Nlm Unique ID:  7905589     Medline TA:  Neurotoxicology     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  167-74     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Checklist
Chi-Square Distribution
Child Behavior*
Child Behavior Disorders / diagnosis,  etiology*,  psychology
Child Development*
Child, Preschool
China
Cross-Sectional Studies
Female
Humans
Internal-External Control*
Logistic Models
Male
Maternal Exposure / adverse effects*
Odds Ratio
Pregnancy
Prenatal Exposure Delayed Effects*
Psychiatric Status Rating Scales
Questionnaires
Risk Assessment
Risk Factors
Tobacco Smoke Pollution / adverse effects*
Young Adult
Grant Support
ID/Acronym/Agency:
K01 ES015877/ES/NIEHS NIH HHS; K01-ES015 877;/ES/NIEHS NIH HHS; K02 ES019878/ES/NIEHS NIH HHS; K02-ES019878-01/ES/NIEHS NIH HHS; R01 ES018858/ES/NIEHS NIH HHS; R01-ES018858/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
0/Tobacco Smoke Pollution
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Visible light-absorbing rhenium(i) tricarbonyl complexes as triplet photosensitizers in photooxidati...
Next Document:  Breast regression protein-39 (BRP-39) promotes dendritic cell maturation in vitro and enhances Th2 i...