| Mortality of twins and singletons by gestational age: a varying-coefficient approach. | |
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MedLine Citation:
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PMID: 11130615 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study used data from the Swedish Medical Birth Registry between 1982 and 1995 to address the question of whether there is higher mortality in twins in relation to singletons of the same gestational age and to examine the optimal gestational age range for twins. A "varying-coefficient approach" was adopted to estimate the gestational age-specific relative and absolute risks of mortality in twins and singletons, adjusting for size at birth and risk factors of short gestational duration. The models showed that twins born between 29 and 37 weeks of gestation had lower mortality than did singletons of the same gestational age. Twins born at older gestational age had higher mortality than did their singleton counterparts, because longer gestational duration was more advantageous to singletons than to twins. Without adjustment for size at birth, there was an upturn of mortality in twins born after 38 weeks. It is postulated that twins have better health than singletons initially, but they could not enjoy the benefit of a longer gestational duration as much as singletons could. The optimal gestational age for twins appeared to be 37-39 weeks according to neonatal and infant mortality. |
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Authors:
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Y B Cheung; P Yip; J Karlberg |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of epidemiology Volume: 152 ISSN: 0002-9262 ISO Abbreviation: Am. J. Epidemiol. Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2000-12-27 Completed Date: 2001-01-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7910653 Medline TA: Am J Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 1107-16 Citation Subset: IM |
Affiliation:
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Clinical Trials Centre, Faculty of Medicine, University of Hong Kong, Pokfulam, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Distribution Cause of Death* Female Gestational Age Humans Infant Mortality / trends* Infant, Newborn Logistic Models Male Multivariate Analysis Pregnancy Registries Risk Factors Statistics, Nonparametric Sweden / epidemiology Twins* |
| Comments/Corrections | |
Comment In:
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Am J Epidemiol. 2000 Dec 15;152(12):1117-9; discussion 1120
[PMID:
11130616
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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