Document Detail

Mortality risks among heavy-smokers with special reference to women: a long-term follow-up of an urban population.
MedLine Citation:
PMID:  17534729     Owner:  NLM     Status:  MEDLINE    
Increased mortality risks associated with smoking are well established among men. There are very few population-based studies comprising a sufficient number of heavily smoking women, measuring the direct effect of smoking on mortality risks. Between 1974 and 1992, 8,499 women and 13,888 men attended a health screening programme including reporting of smoking habits. Individuals were followed for total mortality until 2005. All-cause, cancer, cardiovascular, lung cancer and respiratory mortality were calculated in smoking categories <10 g per day, 10-19 g per day, and > or =20 g per day with never-smokers as a reference group and with adjustments for co-morbidities, socio-economic and marital status. For respiratory mortality and lung cancer adjustments for FEV(1), socio-economic and marital status were performed. Smoking was associated with a two to almost threefold increased mortality risk among women and men. The relative risk (RR) with 95% confidence interval, (CI) for women who smoked 10-19 g per day was 2.44 (2.07-2.87), and for those who smoked 20 g per day or more the RR (95% CI) was 2.42 (2.00-2.92). Smoking was a strong risk factor for cardiovascular mortality among women, the RR (95% CI) for women who smoked 10-19 g per day was 4.52 (3.07-6.64). Ex-smoking women showed increased risks of all-cause mortality; RR (95% CI) 1.26 (1.04-1.52) cancer (excluding lung cancer); RR (95% CI) 1.42 (1.07-1.88) and lung cancer RR (95% CI) 2.71 (1.02-7.23) mortality. However, the cardiovascular; RR (95% CI) 1.18 (0.69-2.00) and respiratory; RR (95% CI) 0.79 (0.16-3.84) mortality risks were not statistically significant. This study confirms that as for men, middle-aged heavily smoking women have a two to threefold increased mortality risk. Adjustments for co-morbidity, socio-economic and marital status did not change these results.
M Ekberg-Aronsson; P M Nilsson; J-A Nilsson; C-G Löfdahl; K Löfdahl
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-05-30
Journal Detail:
Title:  European journal of epidemiology     Volume:  22     ISSN:  0393-2990     ISO Abbreviation:  Eur. J. Epidemiol.     Publication Date:  2007  
Date Detail:
Created Date:  2007-06-06     Completed Date:  2007-09-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508062     Medline TA:  Eur J Epidemiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  301-9     Citation Subset:  IM    
Department of Respiratory Medicine and Allergology, Lund University Hospital, University of Lund, Lund, 221 85, Sweden.
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MeSH Terms
Cardiovascular Diseases / mortality
Lung Diseases / physiopathology
Marital Status
Middle Aged
Respiratory Insufficiency / mortality
Risk Assessment
Smoking / epidemiology,  mortality*
Social Class
Sweden / epidemiology
Urban Population*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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