| Mortality of patients with lone and idiopathic atrial fibrillation is similar to mortality in general population of Serbia. | |
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MedLine Citation:
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PMID: 20337095 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIM: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in general population. The aim of the study was to compare all-cause mortality and cardiovascular mortality in patients with lone and idiopathic AF to correspondent mortality in general population of Serbia. METHODS: A longitudinal observational study included the patients with nonvalvular AF as the main indication for in-hospital and/or outpatient treatment in the Clinical Center of Serbia, during a period 1992-2007, if the latest date of first diagnosed AF was early January 2003; in that way, the total follow-up could last at least 5 years (minimum 1 year prospectively), or until death. Principles of oral anticoagulation, heart rhythm and frequency control during the study period were conducted according to the latest international guidelines for diagnosis and treatment of AF in the study period. Lone and idiopathic AF were defined as AF in patients without any underlying disease, younger than 60 years (lone AF) or older (idiopathic AF). To compare mortality of the study population with mortality of general population we used the standardized mortality ratio (SMR) and chi-square test with p < 0.05 as a level of statistical significance. RESULTS: Out of 442 patients with AF and no underlying disease, aged 47 +/- 12.6 years, with mean follow-up of 11.5 +/- 7.2 years, 12 patients (2.7%) died: 7 patients of non-cardiovascular causes and 5 patients (1.1%) of cardiovascular death. When compared to the general population of Serbia, all-cause mortality and cardiovascular mortality in the patients with lone and idiopathic AF were not higher than in general population (p < 0.05). CONCLUSION: All-cause mortality and cardiovascular mortality of patients with lone and idiopathic AF are similar to all-cause mortality and cardiovascular mortality in general population of Serbia. |
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Authors:
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Tatjana Potpara; Miodrag Gruji?; Jelena Marinkovi?; Bosiljka Vujisi?-Tesi?; Miodrag Ostoji?; Marija Polovina |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Vojnosanitetski pregled. Military-medical and pharmaceutical review Volume: 67 ISSN: 0042-8450 ISO Abbreviation: Vojnosanit Pregl Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-03-26 Completed Date: 2010-04-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 21530700R Medline TA: Vojnosanit Pregl Country: Serbia |
Other Details:
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Languages: eng Pagination: 132-5 Citation Subset: IM |
Affiliation:
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Clinical Center of Serbia, Institute for Cardiovascular Diseases, Belgrade, Serbia. spotpara@sbb.rs |
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| MeSH Terms | |
Descriptor/Qualifier:
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Atrial Fibrillation
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mortality* Cardiovascular Diseases / mortality Cause of Death Humans Longitudinal Studies Middle Aged Mortality Serbia / epidemiology |
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