Document Detail


Mortality of patients with lone and idiopathic atrial fibrillation is similar to mortality in general population of Serbia.
MedLine Citation:
PMID:  20337095     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIM: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in general population. The aim of the study was to compare all-cause mortality and cardiovascular mortality in patients with lone and idiopathic AF to correspondent mortality in general population of Serbia. METHODS: A longitudinal observational study included the patients with nonvalvular AF as the main indication for in-hospital and/or outpatient treatment in the Clinical Center of Serbia, during a period 1992-2007, if the latest date of first diagnosed AF was early January 2003; in that way, the total follow-up could last at least 5 years (minimum 1 year prospectively), or until death. Principles of oral anticoagulation, heart rhythm and frequency control during the study period were conducted according to the latest international guidelines for diagnosis and treatment of AF in the study period. Lone and idiopathic AF were defined as AF in patients without any underlying disease, younger than 60 years (lone AF) or older (idiopathic AF). To compare mortality of the study population with mortality of general population we used the standardized mortality ratio (SMR) and chi-square test with p < 0.05 as a level of statistical significance. RESULTS: Out of 442 patients with AF and no underlying disease, aged 47 +/- 12.6 years, with mean follow-up of 11.5 +/- 7.2 years, 12 patients (2.7%) died: 7 patients of non-cardiovascular causes and 5 patients (1.1%) of cardiovascular death. When compared to the general population of Serbia, all-cause mortality and cardiovascular mortality in the patients with lone and idiopathic AF were not higher than in general population (p < 0.05). CONCLUSION: All-cause mortality and cardiovascular mortality of patients with lone and idiopathic AF are similar to all-cause mortality and cardiovascular mortality in general population of Serbia.
Authors:
Tatjana Potpara; Miodrag Gruji?; Jelena Marinkovi?; Bosiljka Vujisi?-Tesi?; Miodrag Ostoji?; Marija Polovina
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vojnosanitetski pregled. Military-medical and pharmaceutical review     Volume:  67     ISSN:  0042-8450     ISO Abbreviation:  Vojnosanit Pregl     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-26     Completed Date:  2010-04-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21530700R     Medline TA:  Vojnosanit Pregl     Country:  Serbia    
Other Details:
Languages:  eng     Pagination:  132-5     Citation Subset:  IM    
Affiliation:
Clinical Center of Serbia, Institute for Cardiovascular Diseases, Belgrade, Serbia. spotpara@sbb.rs
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / mortality*
Cardiovascular Diseases / mortality
Cause of Death
Humans
Longitudinal Studies
Middle Aged
Mortality
Serbia / epidemiology

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