Document Detail

Mortality and morbidity in extremely preterm infants (22 to 26 weeks of gestation): Austria 1999-2001.
MedLine Citation:
PMID:  16416355     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this retrospective study was to analyze the mortality and morbidity for extremely preterm infants with a gestational age from 22 to 26 weeks. All infants were born in Austria during the years 1999-2001. METHODS: Data were collected from 16 neonatal intensive care units in Austria. Main outcome criteria were mortality, the rates of chronic lung disease (CLD) and severe retinopathy of prematurity (ROP, stage > or =3) to determine the short-term outcome; the rate of cerebral palsy (CP) at the corrected age of twelve months to assess the long-term outcome. RESULTS: Overall, 796 preterm infants with a gestational age less than 27 weeks were born in Austria and 581 (73%) were registered as live-born infants. Of those live born, 508 (87%) were analyzed. The mortality rates were 83%, 76%, 43%, 26% and 13% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. The rates of CLD were 33% (22 weeks), 36% (23 weeks), 42% (24 weeks), 31% (25 weeks) and 22% (26 weeks). The rates of ROP of stage > or =3 were 0% (22 weeks), 29% (23 weeks), 23% (24 weeks), 18% (25 weeks) and 10% (26 weeks). The rates of CP at the corrected age of 12 months were 33%, 50%, 33%, 26% and 25% for 22, 23, 24, 25 and 26 weeks' gestation, respectively. CONCLUSIONS: The results of this national study are in accordance with the international literature: mortality and morbidity increased with decreasing gestational age.
Christina Weber; Manfred Weninger; Katrin Klebermass; Gernot Reiter; Gabriele Wiesinger-Eidenberger; Mathias Brandauer; Raimund Kraschl; Karl Lingitz; Renate Grassl-Jurek; Walter Sterniste; Bernd Balluch; Micha Kolmer; Robert Bruckner; Gerolf Schweintzger; Hans Salzer; Irene Rath; Peter Kubitsch; Werner Zissler; Wilhelm Müller; Berndt Urlesberger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  117     ISSN:  0043-5325     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2006-01-17     Completed Date:  2006-02-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  740-6     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, Medical University of Graz, Graz, Austria.
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MeSH Terms
Age Distribution
Birth Weight*
Cerebral Palsy / mortality*
Cohort Studies
Gestational Age
Infant, Newborn
Infant, Premature, Diseases / epidemiology*
Premature Birth / mortality*
Retrospective Studies
Risk Assessment / methods*
Risk Factors
Sex Distribution
Survival Analysis
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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