Document Detail


Mortality from leukemia after irradiation in infancy for skin hemangioma.
MedLine Citation:
PMID:  8619025     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
From 1920 through 1959, 14,624 infants were exposed to ionizing radiation for skin hemangioma at Radiumhemmet. They were all less than 18 months old (mean 6 months) at the time of first exposure. The irradiated hemangiomas were located all over the body. The weighted bone marrow dose was on average 0.13 Gy (range < 0.01-4.6 Gy). During the period 1920-1986, 20 deaths from leukemia (11 childhood and 9 adult) were observed in the cohort compared with 17 expected during the same period. There were no significant associations between childhood leukemia and radiation dose. Despite the relatively large number of infants studied, the low average dose to bone marrow limited the possibility of detecting a small radiation risk as might be predicted from other radiation studies.
Authors:
M Lundell; L E Holm
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Radiation research     Volume:  145     ISSN:  0033-7587     ISO Abbreviation:  Radiat. Res.     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-06-13     Completed Date:  1996-06-13     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0401245     Medline TA:  Radiat Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  595-601     Citation Subset:  IM; S    
Affiliation:
Department of Hospital Physics, Karolinska Hospital, Stockholm, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Beta Particles
Child
Cohort Studies
Female
Gamma Rays
Hemangioma / radiotherapy*
Humans
Infant
Leukemia, Radiation-Induced / epidemiology,  etiology,  mortality*
Middle Aged
Pregnancy
Prenatal Exposure Delayed Effects
Radiotherapy / adverse effects*
Radium / adverse effects,  therapeutic use
Risk Factors
Skin Neoplasms / radiotherapy*
X-Rays
Chemical
Reg. No./Substance:
7440-14-4/Radium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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