Document Detail


Mortality and causes of death after first ischemic stroke: the Northern Manhattan Stroke Study.
MedLine Citation:
PMID:  11739816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To analyze the early and long-term causes of death after first ischemic stroke in the multiethnic northern Manhattan community. METHODS: In the prospective, population-based Northern Manhattan Stroke Study, 980 patients with first ischemic stroke (mean age 70 years; 56% women; 49% Caribbean Hispanic, 31% black, 20% white) were followed for a mean of 3 years. Causes of death were classified as vascular (incident stroke, recurrent stroke, cardiac) or nonvascular. Life table analyses were used to assess mortality risks among different race-ethnic groups. Early (< or =1 month) vs long-term (> 1 month to 5 years) causes of death were compared. RESULTS: Among the 980 patients followed, 278 (28%) died; 47 (5%) died during the first month. Cumulative mortality risk was 5% at 1 month, 16% after 1 year, 29% after 3 years, and 41% after 5 years. The proportion of vascular deaths among all deaths was 75% at 1 month and 43% thereafter (p = 0.001). Stroke, either incident (53%) or recurrent (4%), caused early deaths in 57% and long-term deaths in 14% (p = 0.001). Overall mortality risks did not differ significantly among race-ethnic groups. However, the proportion of incident stroke-related early deaths was 85% in Caribbean Hispanic patients, 33% in white patients, and 25% in black patients (p = 0.002). CONCLUSIONS: Among patients with first ischemic stroke, incident stroke is the leading cause of early deaths. A large proportion of long-term deaths are nonvascular in origin. Despite similar overall mortality rates in race-ethnic groups, our data suggest a higher incident stroke-related early mortality among Caribbean Hispanics.
Authors:
A Hartmann; T Rundek; H Mast; M C Paik; B Boden-Albala; J P Mohr; R L Sacco
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neurology     Volume:  57     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-12     Completed Date:  2002-01-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2000-5     Citation Subset:  AIM; IM    
Affiliation:
Stroke Center, Department of Neurology, Columbia University College of Physicians and Surgeons and School of Public Health, New York, NY, USA. ahart@zedat.fu-berlin.de
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MeSH Terms
Descriptor/Qualifier:
African Continental Ancestry Group
Aged
Aged, 80 and over
Cause of Death*
Cerebral Infarction / ethnology,  mortality*
Cross-Sectional Studies
European Continental Ancestry Group
Female
Hispanic Americans / statistics & numerical data
Humans
Incidence
Male
Middle Aged
New York City / epidemiology
Prospective Studies
Survival Analysis
Urban Population / statistics & numerical data*
Grant Support
ID/Acronym/Agency:
2 M01 RR00645/RR/NCRR NIH HHS; R01 NS 27517/NS/NINDS NIH HHS; R01 NS 29992/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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