| Mortality associated with congenital syphilis in the United States, 1992-1998. | |
| | |
MedLine Citation:
|
PMID: 11986485 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To summarize national trends in the incidence of congenital syphilis (CS) and associated mortality. METHODS: We analyzed CS surveillance data reported to the Centers for Disease Control and Prevention by 50 states and the District of Columbia from 1992-1998. RESULTS: From 1992-1998, 942 deaths, including 760 stillbirths, were reported among 14 627 cases of CS, yielding a case fatality ratio (stillborns and deaths/all cases) of 6.4%. Untreated, inadequately treated, or undocumented treatment of syphilis during pregnancy accounted for 87.4% of reported cases. Among CS cases, there was an inverse relationship between the number of prenatal care visits (0, 1-4, 5-9, >/=10) and risk of fatal outcome. Among deaths, 52% of deliveries occurred by 30 weeks' gestation. Among live born infants with CS, death occurred more often in infants for whom no radiograph or cerebrospinal fluid evaluation was reported. Although both cases and deaths from CS declined from 1992-1998, there was no significant change in the case fatality ratio. CONCLUSION: Mortality associated with CS continues to be an important public health problem that will resurge if adult syphilis rates increase. Because a large proportion of deaths occur at low gestational age, earlier diagnosis and treatment of maternal syphilis may substantially reduce the case fatality ratio. |
| | |
Authors:
|
Deborah A Gust; William C Levine; Michael E St Louis; Jim Braxton; Stuart M Berman |
Related Documents
:
|
15182475 - Do children have one third less peripheral vision than adults? 3272585 - Intracranial pressure (icp) monitoring as a guide to prognosis in a lightning-injured, ... 15335495 - An analysis and report of custodial deaths in nebraska, usa. 956805 - Phenothiazine death: an unusual case report. 23271995 - Infantile perianal pyramidal protrusion: a report of 8 new cases and a review of the li... 22092575 - The itchy scalp--scratching for an explanation. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Pediatrics Volume: 109 ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 2002 May |
Date Detail:
|
Created Date: 2002-05-02 Completed Date: 2002-05-22 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: United States |
Other Details:
|
Languages: eng Pagination: E79-9 Citation Subset: AIM; IM |
Affiliation:
|
Division of STD Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Atlanta, GA 30333, USA. dgg6@cdc.gov |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Birth Weight Centers for Disease Control and Prevention (U.S.) / statistics & numerical data Female Fetal Death / epidemiology Gestational Age Humans Incidence Infant Infant Mortality / trends Infant, Newborn Male Maternal Age Population Surveillance Pregnancy Pregnancy Complications, Infectious / epidemiology Pregnancy Outcome / epidemiology Prenatal Care Prevalence Syphilis, Congenital / diagnosis, epidemiology*, mortality* United States / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pneumatosis intestinalis after pediatric thoracic organ transplantation.
Next Document: Influenza vaccination coverage level at a cystic fibrosis center.