Document Detail

Morphometric analysis of spinous cell in oral submucous fibrosis. Comparison with normal mucosa, leukoplakia and squamous cell carcinoma.
MedLine Citation:
PMID:  7555236     Owner:  NLM     Status:  MEDLINE    
The morphometric analysis of the spinous cell in 16 specimens of oral submucous fibrosis (OSF) was made by using interactive image analysis system (IBAS-II). 19 parameters of the size and shape were chosen, and compared with normal mucosa, leukoplakia, dysplasia and carcinoma. The results indicated that the cell dimensions (area, perimeter, all kinds of diameter) and nuclear cytoplasmic ratio in OSF were between normal mucosa and dysplasia as well as carcinoma. The former showed a progressive decrease (P < 0.01), and the latter showed a progressive increase (P < 0.01). The dimensions of the nuclei did not show considerable differences among the groups (P < 0.05). A series of discriminant functions had been developed with stepwise discriminant analysis, the agreement ratio for OSF was 93.75%. The decrease of cell area and the increase of nuclear cytoplasmic ratio could reflect a malignant progress. The cell morphometric model could discriminate OSF well from other groups, suggesting that the change of the epithelium in OSF appearing in the spinous cell is specific itself.
S Gao; S Liu; Z Shen; L Peng
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chinese medical journal     Volume:  108     ISSN:  0366-6999     ISO Abbreviation:  Chin. Med. J.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-11-01     Completed Date:  1995-11-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7513795     Medline TA:  Chin Med J (Engl)     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  351-4     Citation Subset:  IM    
Stomatological Hospital, Tianjin Medical University.
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MeSH Terms
Carcinoma, Squamous Cell / pathology*
Cell Nucleus / pathology
Epithelium / pathology
Image Processing, Computer-Assisted
Leukoplakia, Oral / pathology*
Mouth Mucosa / pathology*
Mouth Neoplasms / pathology*
Oral Submucous Fibrosis / pathology*
Retrospective Studies

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