| Morphometric analysis of particulate debris extracted by four different embolic protection devices from coronary arteries, aortocoronary saphenous vein conduits, and carotid arteries. | |
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MedLine Citation:
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PMID: 15950562 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Different embolic protection devices have been introduced for endovascular interventions: filters or balloon occlusion and aspiration systems. Despite widening use in a variety of vascular beds and clinical syndromes, little is known about the particulate burden liberated from different vascular beds and caught by different protection devices. We performed histologic and morphometric analyses of particulate debris captured during stenting of degenerated saphenous vein bypass grafts and native coronary arteries during acute myocardial infarction or during elective intervention and carotid arteries to assess the relative performance of different protection devices. We analyzed 232 interventions (90 saphenous vein bypass grafts, 77 native coronary arteries, and 65 carotid arteries) with 4 different devices (65 FilterWires, 99 Interceptors, 41 GuardWires, and 27 Proxis catheters) using the RapidVue particle analyzer. No difference in embolic volume retrieved was demonstrated between devices in saphenous vein bypass grafts and carotid interventions. A smaller volume of particulate debris was retrieved by the GuardWire compared with the FilterWire and the Proxis catheter in native coronary artery interventions. The Interceptor and the GuardWire captured more smaller particles than did the FilterWire or Proxis catheter. During saphenous vein bypass graft or carotid intervention, different embolic protection strategies were performed similarly. In native coronary artery stenting, however, proximal embolic protection retrieved larger amounts of debris than did distal filters or occlusion devices. These data may allow greater tailoring of embolic protection device development and application in specific anatomic locales. |
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Authors:
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Vu-Hung Quan; Rany Huynh; Philip A Seifert; Arun Kuchela; Wai-Hong Chen; Gabor Sütsch; Andrew C Eisenhauer; Campbell Rogers |
Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study |
Journal Detail:
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Title: The American journal of cardiology Volume: 95 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-06-13 Completed Date: 2005-08-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1415-9 Citation Subset: AIM; IM |
Affiliation:
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Cardiovascular Division (Cardiac Catheterization Laboratory), Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Arterial Occlusive Diseases
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surgery Blood Vessel Prosthesis Implantation / instrumentation Carotid Arteries / pathology*, surgery Coronary Artery Bypass / adverse effects* Coronary Vessels / pathology*, surgery Embolism / etiology, pathology, prevention & control* Filtration / instrumentation Humans Myocardial Ischemia / surgery Reoperation Retrospective Studies Saphenous Vein / pathology*, transplantation Severity of Illness Index Stents Suction / instrumentation Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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