Document Detail


Morphometric analysis of cardiac hypertrophy: left ventricular shape and number of muscle-fiber layers across left ventricular wall.
MedLine Citation:
PMID:  6216626     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Left ventricular hypertrophy was quantitatively analysed in reference to the relation of ventricular shape and intramyocardial muscle-fiber arrangement. The shape of the ventricle was defined by VL/WL, left ventricular capacity ratio. The ratio was depressed in concentric hypertrophy due to pressure overload and elevated in eccentric hypertrophy due to volume overload. Moreover, VL/WL was reversely correlated with Nf, number of muscle-fiber layers across the left ventricular wall. The results supported the following view on the morphogenesis of left ventricular hypertrophy: The muscle fibers show the strained piling vertically across the ventricular wall to cause wall thickening and cavity narrowing in concentric hypertrophy. On the other hand, the muscle fibers are piled strongly in parallel to the ventricular surface in eccentric hypertrophy to result in attenuation of the wall thickness and dilatation of the ventricular cavity.
Authors:
F Tezuka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  138     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1983-01-07     Completed Date:  1983-01-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aortic Valve Insufficiency / complications
Aortic Valve Stenosis / complications
Cardiomegaly / etiology,  pathology*
Humans
Hypertension / complications
Middle Aged
Mitral Valve Insufficiency / complications
Myocardium / pathology*
Organ Size

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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