Document Detail

Morphology of the seminal vesicle of Calomys callosus submitted to experimental chronic alcoholism.
MedLine Citation:
PMID:  11989779     Owner:  NLM     Status:  MEDLINE    
The objective of the present study was to assess the possible toxic effects of chronic alcohol ingestion on the ultrastructure of the lining epithelium of the seminal vesicle of the rodent Calomys callosus, in order to contribute to the understanding of the consequences of alcohol abuse for the morphology of the male reproductive apparatus. Twenty six adult animals aged three months were divided into two experimental groups. The control group received a solid diet (Purina chow) and tap water, and the alcoholic group received the same solid diet and ethanol P.A. diluted 20% in water (v/v). After 210 days of treatment, all animals were anaesthetised, weighed and sacrificed. At the end of treatment, mean body and seminal vesicle weight did not differ between control and alcoholic animals. The epithelial cells of the alcoholic group showed many alterations such as the presence of lipid droplets of different sizes, nuclei with increased peripheral chromatin and greater electrondensity, megamitochondria, and intense dilatation of the cisterns of the granular endoplasmic reticulum. It was concluded that 20% ethanol provokes marked ultrastructural lesions in the seminal vesicle.
M Martinez; E C Mattos; W J Mello; V H Cagnon; F E Martinez
Related Documents :
8617429 - Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular ...
22995059 - The cardiovascular health of urban african americans: diet-related results from the gen...
15044719 - Alcoholic liver disease in rats fed ethanol as part of oral or intragastric low-carbohy...
19770019 - Limettin and furocoumarins in beverages containing citrus juices or extracts.
18387599 - Dose-response study of chronic alcohol induced changes in sleep patterns in rats.
3480869 - Effect of acute and chronic alcohol feeding on prostaglandin e2 biosynthesis in the sma...
19335229 - Panther chameleons, furcifer pardalis, behaviorally regulate optimal exposure to uv dep...
17429919 - Dieting in children: a population-based study in children aged between 9 and 12 years.
24880039 - Beneficial effects of renin-angiotensin system blockers on testicular steroidogenesis.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of submicroscopic cytology and pathology     Volume:  33     ISSN:  1122-9497     ISO Abbreviation:  J. Submicrosc. Cytol. Pathol.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2002-05-06     Completed Date:  2002-10-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8804312     Medline TA:  J Submicrosc Cytol Pathol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  453-61     Citation Subset:  IM    
Department of Morphology and Pathology, Federal University of São Carlos, SP, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Alcoholism / pathology*
Epithelium / ultrastructure
Seminal Vesicles / ultrastructure*
Testosterone / blood
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ultrastructural evaluation of the effects of the contrast media on the rat kidney.
Next Document:  Differential distribution of the fibres of the collagenous and elastic systems and of glycosaminogly...