| Morphology of rat submandibular gland acinar secretory granules and their alteration during the acute phase of experimental Chagas' disease. | |
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MedLine Citation:
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PMID: 8580867 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a morphometric study at the electron microscope level immature submandibular glands of 8 normal male Holtzman rats were compared to those of 12 rats (46 days old) infected with the Y strain of Trypanosoma cruzi at day 18 of infection. In the fasted animals, the acinar cells of controls exhibited a variety of morphological types of immature secretory granules with lamellar substructure composed of swirling cords of electron-dense material, whereas in the infected rats mature secretory granules containing dense aggregates of short or long filamentous material were more abundant. These results suggest an acceleration of acinar maturation in infected animals. |
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Authors:
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J B Alves; M C Ulrich-Karine; M S Alves |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] Volume: 28 ISSN: 0100-879X ISO Abbreviation: Braz. J. Med. Biol. Res. Publication Date: 1995 Jul |
Date Detail:
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Created Date: 1996-03-19 Completed Date: 1996-03-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8112917 Medline TA: Braz J Med Biol Res Country: BRAZIL |
Other Details:
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Languages: eng Pagination: 761-6 Citation Subset: IM |
Affiliation:
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Departamento de Morfologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Animals Chagas Disease / pathology* Male Rats Rats, Sprague-Dawley Submandibular Gland / ultrastructure* |
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