Document Detail


Morphology evaluation of primary enamel exposed to antihistamine and fluoride dentifrice--an in vitro study.
MedLine Citation:
PMID:  16494116     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This in vitro study sought to evaluate the action of a pediatric medication with low pH and high acidity in primary enamel submitted (or not) to daily applications of fluoride dentifrice. For this study, 70 blocks of primary molars (n = 10 per subgroup) were analyzed using scanning electron microscopy. Six subgroups (two control and four experimental) were submitted to different treatments for 10 days. Microscopically, the enamel blocks of the subgroups that received medication and fluoride demonstrated the largest areas of partially or totally conditioned superficial enamel. The opposite was observed in the subgroups that were not exposed to fluoride; erosions in the internal enamel and in the transition zone between deep enamel and dentine showed superior percentiles. It was concluded that the medication modified the morphology of the primary enamel and that the use of fluoride was able to reduce the erosive effect of the formulation.
Authors:
Covolo Carolina da Costa; Izabel Cristina Santos Almeida; Luiz Cesar da Costa Filho; Hugo Mitsuo Silva Oshima
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  General dentistry     Volume:  54     ISSN:  0363-6771     ISO Abbreviation:  Gen Dent     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-02-23     Completed Date:  2006-05-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610466     Medline TA:  Gen Dent     Country:  United States    
Other Details:
Languages:  eng     Pagination:  21-7     Citation Subset:  D    
Affiliation:
Post Graduate Program in Dentistry, Federal University of Santa Catarina, Florianopolis, SC, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Cariostatic Agents / pharmacology
Dental Enamel / drug effects*,  ultrastructure
Dental Enamel Solubility
Dentifrices / pharmacology
Fluorides / pharmacology
Histamine H1 Antagonists, Non-Sedating / adverse effects*
Humans
Hydrogen-Ion Concentration
Loratadine / adverse effects*
Microscopy, Electron, Scanning
Molar
Statistics, Nonparametric
Tooth Demineralization / prevention & control
Tooth Erosion / chemically induced*,  prevention & control
Tooth, Deciduous / drug effects*
Chemical
Reg. No./Substance:
0/Cariostatic Agents; 0/Dentifrices; 0/Fluorides; 0/Histamine H1 Antagonists, Non-Sedating; 79794-75-5/Loratadine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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