Document Detail

Morphology of coronary heart disease (author's transl)
MedLine Citation:
PMID:  1265248     Owner:  NLM     Status:  MEDLINE    
Atherosclerosis and insufficiency of the coronary arteries and their sequelae are summarized in the term "coronary heart disease". For the evaluation of the coronary arteries the knowledge of malformations, variants and supply areas is of importance. Extension and severity of atherosclerosis of the coronary arteries and their insufficiency is being influenced by hyperlipidemia, hypertension and diabetes mellitus. The process of atherosclerosis as a cause of the proliferation of vascular smooth muscle cells in complicated by ulceration, parietal and obliterative thrombosis as well by intramural hemorrhages. Relative ischemia leeds to disseminated cell necrosis; total ischemia causes large myocardial tissue necrosis, called infarction. Localization and extension of infarction and the later scars correspond to the caliber of the obliterated coronary artery and to the significance of the collaterals. Postmortem coronary angiography can detect cause and extension of the damaged cardiac area. Functional significance of chronic coronary heart disease is related to the "critical connective tissue content" of the heart. After surgical treatment qualitative and quantitative morphology may help to explain postoperative cardiac failure.
H J Knieriem
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Der Radiologe     Volume:  16     ISSN:  0033-832X     ISO Abbreviation:  Radiologe     Publication Date:  1976 Mar 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401257     Medline TA:  Radiologe     Country:  GERMANY, WEST    
Other Details:
Languages:  ger     Pagination:  84-8     Citation Subset:  IM    
Vernacular Title:
Morphologische Grundlagen der coronaren Herzerkrankung
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MeSH Terms
Arteries / abnormalities
Arteriosclerosis / complications,  pathology
Chronic Disease
Coronary Angiography
Coronary Disease / complications,  pathology*
Coronary Vessel Anomalies
Diabetic Angiopathies / pathology
Hyperlipidemias / complications
Hypertension / complications
Middle Aged
Muscle, Smooth / pathology
Myocardium / pathology

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