Document Detail

Morphological and quantitative aspects of the development of cytoplasmic granules in concanavalin A-stimulated normal human lymphocytes.
MedLine Citation:
PMID:  1693648     Owner:  NLM     Status:  MEDLINE    
We have studied normal human lymphocytes stimulated by concanavalin A to determine the rate and extent of development of cytoplasmic granules. Morphological studies on stimulated lymphocytes were undertaken at the light and electron microscopic level. The percentage of T lymphocytes bearing different CD antigens (CD3, CD4, and CD8) that also contained cytoplasmic granules was also assessed. Granules were identified in a high percentage of lymphocytes bearing each of the three CD markers studied.
A McGirl; G Shea; M Melinn; H McLaughlin
Related Documents :
7003028 - Identification of t & b lymphocytes on skin sections from patients with lymphoprolifera...
163788 - Stimulation of human lymphocytes by herpes simplex virus antigens.
1830628 - Effects of deoxyadenosine on ribonucleotide reductase in adenosine deaminase-deficient ...
3071478 - Labelling of a t lymphocyte subpopulation with monoclonal antibody bound to colloidal g...
10458988 - Antigenic variation in plasmodium falciparum: mechanisms and consequences.
9276428 - Stabilities of free and complexed human immunodeficiency virus p24 antigens during shor...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of leukocyte biology     Volume:  47     ISSN:  0741-5400     ISO Abbreviation:  J. Leukoc. Biol.     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-07-13     Completed Date:  1990-07-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405628     Medline TA:  J Leukoc Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  514-8     Citation Subset:  IM    
Department of Pathology, University College Dublin, Ireland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cell Survival / drug effects,  physiology
Concanavalin A / pharmacology*
Cytoplasmic Granules / physiology,  ultrastructure*
Lymphocyte Activation / physiology*
Microscopy, Electron / methods
Staining and Labeling
T-Lymphocytes / drug effects*,  physiology,  ultrastructure
Reg. No./Substance:
11028-71-0/Concanavalin A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Surface phenotype analysis of human monocyte to macrophage maturation.
Next Document:  Modification of the core lipids of low density lipoproteins produces selective alterations in the ex...