Document Detail

Morphological investigations of mixed pituitary adenomas.
MedLine Citation:
PMID:  6421097     Owner:  NLM     Status:  MEDLINE    
Thirteen pituitary adenomas were investigated by light and electron microscopy and in tissue culture. In all adenomas the production of growth hormone and prolactin was proved by endocrine symptoms of the patients and by laboratory tests. Histopathological findings were compared with culture characteristics. In 3 cases the adenoma consisted of three kinds of cell population, in 7 cases of two kinds, and in other 3 cases of one kind. In cases where 3 kinds of cell population were found, beside the granulated cells star-shaped forms without secretion granules could be observed. They probably corresponded to follicular cells. In three cases one single cell population was found. In these cases two different hormones might have been produced by one type of cell. These cells could be considered stem-like cellular elements or differentiated committed cells.
F Slowik; L Gazsó; E Pásztor; P Piffkó; K Lapis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta morphologica Hungarica     Volume:  31     ISSN:  0236-5391     ISO Abbreviation:  Acta Morphol Hung     Publication Date:  1983  
Date Detail:
Created Date:  1984-03-22     Completed Date:  1984-03-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8307964     Medline TA:  Acta Morphol Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  353-64     Citation Subset:  IM    
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MeSH Terms
Adenoma / pathology*,  secretion,  ultrastructure
Cells, Cultured
Growth Hormone / secretion*
Microscopy, Electron
Pituitary Neoplasms / pathology*,  secretion,  ultrastructure
Prolactin / secretion*
Reg. No./Substance:
9002-62-4/Prolactin; 9002-72-6/Growth Hormone

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