Document Detail

Morphological and histopathological aspects of aneurysms after patch aortoplasty for coarctation.
MedLine Citation:
PMID:  2146929     Owner:  NLM     Status:  MEDLINE    
Repair of coarctation of the aorta by synthetic patch grafting has been complicated by late aneurysm formation. These aneurysms differ macroscopically from atherosclerotic thoracic aortic dilatations. Specimens for microscopic examination were taken from 14 of 20 patients undergoing aneurysm resection. Histological analysis of the specimens showed medionecrosis in 13 patients of the specimens showed medionecrosis in 13 patients (93%), foreign body reaction in 11 patients (78%), and intimal thickening in 3 patients (21%). The three layers of the aortic wall could be identified in the aneurysms. On the basis of these results, we discuss the etiologic factors and pathogenetic mechanisms involved in the development of these aneurysms.
L Heikkinen; H Sariola; J Salo; K Ala-Kulju
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  50     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1990-12-26     Completed Date:  1990-12-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  946-8     Citation Subset:  AIM; IM    
Department of Thoracic and Cardiovascular Surgery, Helsinki University Central Hospital, Finland.
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MeSH Terms
Anastomosis, Surgical
Aorta / surgery*
Aortic Aneurysm / etiology,  pathology*
Aortic Coarctation / surgery*
Blood Vessel Prosthesis / adverse effects*
Cicatrix / pathology
Elastic Tissue / pathology
Foreign-Body Reaction / etiology,  pathology
Muscle, Smooth, Vascular / pathology
Polyethylene Terephthalates / adverse effects
Polytetrafluoroethylene / adverse effects
Reg. No./Substance:
0/Polyethylene Terephthalates; 9002-84-0/Polytetrafluoroethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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