Document Detail

Morphological findings in apparently idiopathic ventricular tachycardia. An echocardiographic haemodynamic and histologic study.
MedLine Citation:
PMID:  4029188     Owner:  NLM     Status:  MEDLINE    
In order to investigate the anatomic substrate of 'idiopathic' ventricular tachycardia (VT) 10 patients with chronic recurrent VT and no apparent sign of heart disease underwent an echocardiographic, haemodynamic and histologic study (5 males, 5 females: mean age = 40 +/- 11 years). In the patients with a left bundle branch block morphology of VT (7 cases), four showed findings compatible with an arrhythmogenic right ventricular dysplasia or a right ventricular cardiomyopathy. In the other three all examinations were normal with the exception of endomyocardial biopsy, which showed slight non specific changes in two. Of the remaining 3 cases (characterized by a right bundle branch block morphology of VT or by the presence of polymorphic VT) one had histologic evidence of myocarditis while another developed dilated cardiomyopathy. Macroscopic and/or microscopic ventricular abnormalities are frequently found in patients with VT which appears idiopathic. In these cases myocardial disease is frequently progressive, despite optimal control of VT.
T Morgera; A Salvi; E Alberti; F Silvestri; F Camerini
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  6     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1985 Apr 
Date Detail:
Created Date:  1985-10-16     Completed Date:  1985-10-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  323-34     Citation Subset:  IM    
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MeSH Terms
Amiodarone / therapeutic use
Bundle-Branch Block / pathology
Cardiomyopathies / pathology
Drug Therapy, Combination
Follow-Up Studies
Heart Ventricles / pathology
Hemodynamics* / drug effects
Middle Aged
Myocarditis / pathology
Myocardium / pathology
Pacemaker, Artificial
Tachycardia / drug therapy,  pathology*
Verapamil / therapeutic use
Reg. No./Substance:
1951-25-3/Amiodarone; 52-53-9/Verapamil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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