Document Detail


Morphological features of coronary arteries and lesions in hearts from five species of sharks collected from the northwestern Atlantic Ocean.
MedLine Citation:
PMID:  22882583     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Morphological features of coronary arteries and incidental lesions are reported from hearts in five species of sharks, the shortfin mako shark, Isurus oxyrhinchus Rafinesque, thresher shark Alopias vulpinus (Bonaterre), blue shark, Prionace glauca L., the smooth dogfish, Mustelus canis (Mitchill), and spiny dogfish, Squalus acanthias L. Sharks were collected from the northwestern Atlantic between June and August from 1996 to 2010. They were necropsied dockside and the hearts were preserved in buffered formalin. Routine sections including ventricle/conus arteriosus and the atrio-ventricular junctions were embedded in paraffin, stained with common histological and immunohistochemical methods and examined by brightfield microscopy. Myointimal hyperplasia, medial myo-myxomatous hyperplasia and bifurcation pads were observed commonly, and medial muscle reorientation and epicardial myeloid tissues were rare. All the above features differed in severity, prevalence and distribution depending on anatomical site and shark species/size. Morphometric analysis indicated that myomyxomatous hyperplasia is associated with luminal narrowing of blood vessels. As suggested previously, the described morphological features are most likely physiological responses to blood flow characteristics. Vascular and cardiac lesions were uncommon and included, granulomatous proliferative epicarditis with fibroepitheliomas, myxomatous epicardial expansions, medial arterial vacuolation, myocardial fibrosis, acute ventricular emboli and parasitic granulomas. The lesions of embolism, proliferative and granulomatous epicarditis and myocardial fibrosis were in all sharks associated with capture events including retained fishing hooks. The significance and aetiopathogenesis of medial vacuolation and epicardial myxomatous expansions remains unclear.
Authors:
J D Borucinska; O A Obasa; N M Haffey; J P Scott; L N Williams; S M Baker; S J Min; A Kaplan; R Mudimala
Related Documents :
16631663 - Neovasculogenic therapy to augment perfusion and preserve viability in ischemic cardiom...
19890913 - Chondroitin sulfate expression is required for cardiac atrioventricular canal formation.
8054253 - Preliminary investigation of the efficacy of sublingual verapamil in the management of ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-7
Journal Detail:
Title:  Journal of fish diseases     Volume:  -     ISSN:  1365-2761     ISO Abbreviation:  J. Fish Dis.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9881188     Medline TA:  J Fish Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Blackwell Publishing Ltd.
Affiliation:
Department of Biology, University of Hartford, West Hartford, CT, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A randomized double-blinded placebo-controlled study to evaluate an effective ciclosporin dose for t...
Next Document:  Temperature response of carbon isotope discrimination and mesophyll conductance in tobacco.