Document Detail


Morphological evidence for secondary vestibular afferent connections to the dorsal cochlear nucleus in the rabbit.
MedLine Citation:
PMID:  11602803     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An analysis of central afferent projections to the dorsal cochlear nucleus (dCo), one of the three target nuclei of the auditory nerve, was made using retrograde axonal tracer, wheat germ agglutinin-horseradish peroxidase (WGA-HRP) in the rabbit. The findings showed that, in addition to its afferents from the brainstem auditory nuclei (they are not described herein), the dCo received sparse bilateral connections from the caudal three quarters of the vestibular nuclear complex (VNC). Following selective iontophoretic injections of WGA-HRP into the dCo, a small number of labelled neurones (from 2 to 28 per case) was found in the rostral and caudal portions of the medial vestibular nucleus and in the inferior vestibular nucleus. These neurones were observed mainly in the lateral regions of the nuclei. No labelling appeared in other nuclei which belonged to the VNC. The secondary vestibulocochlear connections have not been reported before in any species. With the anatomical method used, however, their functional role is difficult to explain. Further study is necessary to identify the type of neurotransmitter as well as the physiological properties of vestibular neurones projecting to the dCo, in terms of their responses to a change of the head position and to sound.
Authors:
D Bukowska
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cells, tissues, organs     Volume:  170     ISSN:  1422-6405     ISO Abbreviation:  Cells Tissues Organs (Print)     Publication Date:  2002  
Date Detail:
Created Date:  2001-10-16     Completed Date:  2001-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100883360     Medline TA:  Cells Tissues Organs     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  61-8     Citation Subset:  IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Affiliation:
Department of Neurobiology, University School of Physical Education, Poznań, Poland. bukowska@awf.poznan.pl
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MeSH Terms
Descriptor/Qualifier:
Afferent Pathways / anatomy & histology*
Animals
Cochlear Nucleus / anatomy & histology*
Histocytological Preparation Techniques
Neurons / cytology
Rabbits
Vestibular Nuclei / anatomy & histology*
Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate / analysis
Chemical
Reg. No./Substance:
0/Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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