Document Detail

Morphological definition of a case of 'usual' interstitial pneumonia.
MedLine Citation:
PMID:  550969     Owner:  NLM     Status:  MEDLINE    
A 61-year-old Caucasian female complained of shortness of breath, fever, and a period of rapid weight loss. After routine studies, the patient underwent an open lung biopsy in order to define the characteristics of the interstitial lung disease, and initiate appropriate therapeutic intervention. Typical fibrotic and cellular proliferation were evident in the parenchyma, as determined by standard light microscopy. However, in a correlated study using light microscopy of plastic embedded tissue, as well as scanning and transmission electron microscopy, a major proliferating cell type was identified as a type II pneumocyte. These cells were the predominant lining cells of the alveoli and clearly protruded into and limited available respiratory air spaces. The predominance of type II pneumocytes in the pathogenesis of certain respiratory diseases requires that a better explanation be sought for this phenomenon.
R F Dodson; M G Williams; G A Hurst; G O Crisp
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cytobios     Volume:  26     ISSN:  0011-4529     ISO Abbreviation:  Cytobios     Publication Date:  1979  
Date Detail:
Created Date:  1980-11-24     Completed Date:  1980-11-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207227     Medline TA:  Cytobios     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  131-5     Citation Subset:  IM    
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MeSH Terms
Lung / pathology*
Middle Aged
Pulmonary Alveoli / pathology
Pulmonary Fibrosis / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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