| Morphological changes after percutaneous transluminal angioplasty. | |
| | |
MedLine Citation:
|
PMID: 10199293 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Percutaneous transluminal angioplasty (PTA) dilates constricted arteries at the circle of Willis to reverse cerebral ischemia caused by cerebral vasospasm. Although 90% of the patients show angiographic improvement after PTA, only 70% show clinical improvement. Why some patients do not improve after PTA is unknown. We report on a 48-year-old woman who failed to improve after PTA and died from aneurysm rerupture. Pathologic studies were performed to determine why PTA failed to reverse the symptoms of cerebral ischemia. METHODS: The arteries of the brain were studied by light microscopy using Gomori's trichrome stain. The arteries were also studied by scanning and transmission electron microscopy. RESULTS: The arteries that were dilated with PTA showed compression of the connective tissue, stretching of the internal elastic lamina, and a combination of compression and stretching of the smooth muscle. The small arteries and arterioles that had been treated with an infusion of intraarterial papaverine were constricted with a thickened intimal layer. CONCLUSION: The persistence of cerebral vasospasm in small and perforating arteries may contribute to the failure of cerebral ischemia to reverse after PTA. |
| | |
Authors:
|
A Y Zubkov; A I Lewis; D Scalzo; D H Bernanke; H L Harkey |
Related Documents
:
|
6160743 - Experimental angioplasty: lessons from the laboratory. 2949063 - Percutaneous transluminal angioplasty of the vertebral artery. a therapeutic alternativ... 1416703 - Limb exsanguination. i. the arm: effect of angle of elevation and arterial compression. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Surgical neurology Volume: 51 ISSN: 0090-3019 ISO Abbreviation: Surg Neurol Publication Date: 1999 Apr |
Date Detail:
|
Created Date: 1999-04-16 Completed Date: 1999-04-16 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0367070 Medline TA: Surg Neurol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 399-403 Citation Subset: IM |
Affiliation:
|
Department of Neurosurgery, The University of Mississippi Medical Center, Jackson 39216-4505, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angioplasty, Balloon* Autopsy Brain Ischemia / etiology, pathology*, therapy* Cerebral Angiography Female Humans Ischemic Attack, Transient / complications, pathology*, therapy* Microscopy, Electron Middle Aged Ultrasonography, Doppler, Transcranial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A prospective study on the effects of early surgery on vasospasm after subarachnoid hemorrhage.
Next Document: Non-anastomotic bypass surgery for childhood moyamoya disease using dural pedicle insertion over the...