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Morphological Study of Carotid Artery of WHHL Rabbit after Balloon Dilatation.
MedLine Citation:
PMID:  20673470     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Summary: We performed balloon dilatation in the carotid artery of WHHL rabbits and examined subsequent morphological alteration over time. The balloon was inserted as far as the carotid bifurcation and observations were made on the morphological alteration after dilatation in the atherosclerotic intimal thickening from immediately after balloon dilatation over a period of ten months. Immediately after balloon dilatation, endothelial cells came of circularly and stretching, fragmentation off elastic fibers and coming off of smooth muscle cells of the media were confirmed. No change in the degree of thickening after dilatation was seen in the atherosclerotic intimal thickening of the carotid bifurcation. Three weeks later, endothelium covering except some parts, circular neointima and fibrosis of the media were observed; foamy cells had accumulated in the upper layer of the atherosclerotic intimal thickening, and that region was not yet covered with endothelial cells. The progress of fibrous intimal thickening so as to keep the lumen smooth was seen up to six months later, but foamy cells were not found in the neointima.
Authors:
T Yokouchi; S Iwabuchi; A Tomiyama; H Samejima; K Takahashi; M Shiomi
Publication Detail:
Type:  Journal Article     Date:  2001-05-15
Journal Detail:
Title:  Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences     Volume:  4 Suppl 1     ISSN:  1591-0199     ISO Abbreviation:  Interv Neuroradiol     Publication Date:  1998 Nov 
Date Detail:
Created Date:  2010-08-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9602695     Medline TA:  Interv Neuroradiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  183-6     Citation Subset:  -    
Affiliation:
The Second Department of Neurosurgery, Toho University School of Medicine; Tokyo, Japan.
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