Document Detail


Morphologic Features of Cardiac Sarcoidosis in Native Hearts of Patients Having Cardiac Transplantation.
MedLine Citation:
PMID:  24393258     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Described herein are 10 patients who underwent cardiac transplantation (CT) for severe chronic systolic heart failure resulting from cardiac sarcoidosis. None had the diagnosis of sarcoidosis established before CT except for the 3 patients who earlier had had a portion of left ventricular wall excised for insertion of a left ventricular assist device and non-caseating granulomas were present in the removed myocardium. Although none of the 10 patients had significant narrowing of any of the epicardial coronary arteries, all had focal scarring of the walls of the left and right ventricles and ventricular septum and all had dilated ventricular cavities. The patients with the most ventricular wall scarring tended to have the fewest sarcoid granulomas in the ventricular walls. Two patients had no sarcoid granulomas in the excised heart although one did have typical sarcoid granulomas in the portion of left ventricular wall excised to insert a left ventricular assist device. Patients with cardiac sarcoidosis severe enough to warrant CT had characteristic cardiac ventricular morphologic findings, and no dysfunction of other non-cardiac organs, making clinical diagnosis of cardiac sarcoidosis rather difficult.
Authors:
William C Roberts; Monica S Chung; Jong Mi Ko; John E Capehart; Shelley A Hall
Related Documents :
22965998 - Pre-explant stability of unloading-promoted cardiac improvement predicts outcome after ...
24893938 - Heart failure with preserved ejection fraction: current understandings and challenges.
24892768 - The relationship between fragmentation on electrocardiography and in-hospital prognosis...
24502608 - Effects of av delay and vv delay on left atrial pressure and waveform in ambulant heart...
10626748 - Thrombotic risk associated with the use of iodinated contrast media in interventional c...
17137848 - Suicide by tapestry needle.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-11-23
Journal Detail:
Title:  The American journal of cardiology     Volume:  -     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2013 Nov 
Date Detail:
Created Date:  2014-1-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Predictors of Reperfusion Delay in Patients With ST Elevation Myocardial Infarction Self-Transported...
Next Document:  Association Between Resting Heart Rate and Inflammatory Biomarkers (High-Sensitivity C-Reactive Prot...