Document Detail


Morphogenesis of the secondary palate in normal and hydrocortisone-treated hamsters.
MedLine Citation:
PMID:  943865     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fetal palate morphogenesis was studied in normal and hydrocortisone-treated hamsters. Formation of the normal palate was completed between day 12:00 and 13:00 of gestation, and during this period 8 distinct developmental stages were recognized. Following hydrocortisone administration the early stages, during which vertical-to-horizontal shelf reorientation occurs, appeared to be unaffected, but subsequent fusion between opposing shelves was inhibited. Both chronological age and fetal weight provided reliable criteria for stages of normal palatal development. Following hydrocortisone administration, however, fetal weight was a poorer indicator of stage of palate organogenesis than chronological age.
Authors:
R M Shah; A A Travill
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Teratology     Volume:  13     ISSN:  0040-3709     ISO Abbreviation:  Teratology     Publication Date:  1976 Feb 
Date Detail:
Created Date:  1976-05-10     Completed Date:  1976-05-10     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0153257     Medline TA:  Teratology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  71-83     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Drug-Induced*
Animals
Body Weight
Cleft Palate / chemically induced,  embryology
Cricetinae
Female
Fetus / anatomy & histology
Gestational Age
Hydrocortisone / toxicity*
Male
Morphogenesis / drug effects
Pregnancy
Time Factors
Chemical
Reg. No./Substance:
50-23-7/Hydrocortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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