| Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains. | |
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MedLine Citation:
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PMID: 22179854 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We have examined the addition of Escherichia coli to the diet at day 0 of adult life of females from two Oregon R Drosophila melanogaster strains, selected for different longevities: a short-life with an average adult life span of 10 days and a long-life standard R strain with an average adult life span of 50 days. The addition of bacteria to the diet significantly prolonged the fly longevity in both strains and affected the structure and histochemical reactivity of the fat body. The increased survival was characterized by great amount of glycogen accumulated in fat body cells from both strains. In aged control animals, fed with standard diet, lipid droplets were seen to be stored in fat body of short-lived, but not long-lived, flies. On the whole, our data indicate that exogenous bacteria are able to extend the survival of Drosophila females, and suggest that such a beneficial effect can be mediated, at least in part, by the fat body cells that likely play a role in modulating the accumulation and mobilization of reserve stores to ensure lifelong energy homeostasis. |
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Authors:
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Antonella Franchini; Mauro Mandrioli; Claudio Franceschi; Enzo Ottaviani |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-17 |
Journal Detail:
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Title: Journal of molecular histology Volume: - ISSN: 1567-2387 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101193653 Medline TA: J Mol Histol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Biology, University of Modena and Reggio Emilia, Via Campi 213/D, 41125, Modena, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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