| Morphine in tardive and idiopathic dystonia (short communication). | |
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MedLine Citation:
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PMID: 11716139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Opioids have been shown to improve L-Dopa induced dyskinesias in patients with Parkinson's disease. In this pilot trial of five patients with tardive and four patients with idiopathic dystonia we tested the effect of morphinsulfate in a retarded form with a dosage of 20-60 mg per day. A substantial improvement of dystonic movements could be observed in four patients with tardive and one patient with idiopathic dystonia. The effect was only transient in tardive dystonia while pain relief mediated by morphine overlasted the effect on involuntary movements. |
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Authors:
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D Berg; G Becker; M Naumann; K Reiners |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of neural transmission (Vienna, Austria : 1996) Volume: 108 ISSN: 0300-9564 ISO Abbreviation: J Neural Transm Publication Date: 2001 |
Date Detail:
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Created Date: 2001-11-21 Completed Date: 2002-04-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9702341 Medline TA: J Neural Transm Country: Austria |
Other Details:
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Languages: eng Pagination: 1035-41 Citation Subset: IM |
Affiliation:
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Department of Neurology, University of Würzburg, Federal Republic of Germany. daniela.berg@mail.uni-wuerzburg.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Dose-Response Relationship, Drug Dyskinesia, Drug-Induced / drug therapy*, physiopathology Dystonia / drug therapy*, physiopathology Female Humans Levodopa / adverse effects* Middle Aged Morphine / adverse effects, therapeutic use* Neostriatum / drug effects, metabolism, physiopathology Pain / drug therapy*, etiology, physiopathology Parkinson Disease / drug therapy*, physiopathology Pilot Projects Receptors, Dopamine / drug effects, metabolism Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Levodopa; 0/Receptors, Dopamine; 57-27-2/Morphine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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