Document Detail


Morning glory disk anomaly, choroidal coloboma, and congenital constrictive malformations of the internal carotid arteries (moyamoya disease).
MedLine Citation:
PMID:  10779846     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To report a patient with congenital constrictive malformations of the internal carotid arteries and a morning glory disc anomaly (MGDA). METHODS: Descriptive case report. RESULTS: A 14-year-old girl underwent serial ophthalmologic examinations since the age of seven years because of blurred vision and floaters. A right optic disk anomaly was present that was most compatible with an MGDA accompanied by an inferior choroidal coloboma. Because of the association of such disc malformations with moyamoya disease, the patient underwent cerebral MRI and MRA that showed narrowing of both internal carotid arteries, a finding consistent with early-stage moyamoya disease. CONCLUSION: This case illustrates the importance of recognizing the association of MGDA with moyamoya disease, a treatable condition that may have devastating neurological consequences.
Authors:
C Krishnan; A Roy; E Traboulsi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ophthalmic genetics     Volume:  21     ISSN:  1381-6810     ISO Abbreviation:  Ophthalmic Genet.     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-07-12     Completed Date:  2000-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9436057     Medline TA:  Ophthalmic Genet     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  21-4     Citation Subset:  IM    
Affiliation:
Department of Pediatric Ophthalmology, Cleveland Clinic, The Center for Genetic Eye Diseases, The Cole Eye Institute, Cleveland, Ohio 44124, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Carotid Arteries / pathology,  radiography
Choroid / abnormalities*
Coloboma / complications*
Female
Humans
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Moyamoya Disease / complications*,  diagnosis
Optic Disk / abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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