Document Detail

The Morfeo Study: A 1-year follow-up of complications of vegetative state in a dedicated facility.
MedLine Citation:
PMID:  20235764     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: Vegetative State (VS) implies significant issues. The aim of the MORFEO study is to identify the most relevant complications in VS patients and to supply clinicians and policy-makers with data derived from the analysis of a cohort of patients treated in a dedicated long-term facility setting.
METHODS: A cohort of 22 VS patients treated between 2003 and 2007 were enrolled and followed up for 1 year. The information recorded were: Disability Rating Scale (DRS), Levels of Cognitive Functioning (LCF), pressure sores, nutritional status, neurological complications, articular complications (passive range of motion-ROM), deep-vein thrombosis and infections. The Kolmogorov-Smirnov test was used to verify the normal distribution of the variables. The indicators of complications were analysed with the Friedman test (continuous variables) and with the Cochran Q test (dichotomous variables).
RESULTS: DRS and LCF values showed no significant variation. The number of pressure sores decreased. The nutritional status remained satisfying. The ROM worsened in lower limb joints; a trend (p = ns) towards an improved range was observed in shoulders and elbows. Fifteen infections were recorded.
CONCLUSIONS: The data that proved significant suggest a minimum set of quality-of-care indicators in VS patients: pressure sores follow-up, nutritional status, ROM and incidence of infections.
G Fabbri; M P Fantini; F Buggi; E Carretta; L Lorenzini; R Piperno; N Matera; M R Leo; D L Coulter
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain injury     Volume:  24     ISSN:  1362-301X     ISO Abbreviation:  Brain Inj     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-18     Completed Date:  2010-08-13     Revised Date:  2014-11-14    
Medline Journal Info:
Nlm Unique ID:  8710358     Medline TA:  Brain Inj     Country:  England    
Other Details:
Languages:  eng     Pagination:  620-4     Citation Subset:  IM    
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MeSH Terms
Follow-Up Studies
Infection / etiology*
Middle Aged
Nutritional Status*
Persistent Vegetative State / complications*,  physiopathology
Pressure Ulcer / etiology*
Range of Motion, Articular / physiology*
Statistics, Nonparametric

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