Document Detail

More medications, fewer pills: combination medications for the treatment of hypertension.
MedLine Citation:
PMID:  17534465     Owner:  NLM     Status:  MEDLINE    
Achieving blood pressure targets in hypertension can be challenging. Often, patients require multiple medications to reach these targets. The Canadian Hypertension Education Program has updated its past recommendations to reflect current knowledge regarding effective antihypertensive combinations. Evidence for the use of specific drug combinations in achieving blood pressure targets has been reviewed, and the inventory of effective drug combinations has been expanded. From a clinical perspective, fixed-dose antihypertensive combinations offer certain advantages in terms of efficacy, adherence, cost, convenience, patient-perceived 'wellness' and side effects. Consequently, in the future, fixed-dose combination formulations are likely to become increasingly used in the treatment of cardiovascular disease.
Richard Lewanczuk; Sheldon W Tobe
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  23     ISSN:  0828-282X     ISO Abbreviation:  Can J Cardiol     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-05-30     Completed Date:  2007-07-17     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  573-6     Citation Subset:  IM    
Department of Midicine, University of Alberta, Edmonton, Alberta.
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MeSH Terms
Antihypertensive Agents / administration & dosage,  therapeutic use*
Drug Therapy, Combination
Hypertension / drug therapy*
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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