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More may be less: increasing extracorporeal blood flow in an axillary arterio-arterial access decreases effective clearance.
MedLine Citation:
PMID:  21543661     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Axillary arterio-arterial graft interposition has been described as a reasonable haemodialysis access in selected patients. In a patient with this unusual access, we measured and calculated effective clearance at different extracorporeal blood flows (Q(b)). Effective clearance increased with increasing blood flow and reached a maximum at a Q(b) of ∼200 mL/min but then decreased when Q(b) was increased further. As this type of access typically provides low access flow, one has to be aware that local recirculation will easily occur. Therefore, a Q(b) above access flow has to be avoided since any increase beyond that threshold reduces effective clearance.
Authors:
Peter Krisper; Elisabeth Martinelli; Edda Zierler; Gernot Schilcher; Kurt Tiesenhausen; Daniel Schneditz
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-4
Journal Detail:
Title:  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association     Volume:  -     ISSN:  1460-2385     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706402     Medline TA:  Nephrol Dial Transplant     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
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