| A more comprehensive and highly practical solution to enantioselective aldehyde crotylation. | |
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MedLine Citation:
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PMID: 21486033 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The enantioselective crotylation of aldehydes with 1,2-diaminochlorocrotylsilane reagents is effectively catalyzed by Sc(OTf)(3). The one significant limitation on the utility of these reagents--substrate scope--has thus been addressed. The net result is the most comprehensive and highly practical method for enantioselective aldehyde crotylation yet advanced. |
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Authors:
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Hyunwoo Kim; Stephen Ho; James L Leighton |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2011-04-12 |
Journal Detail:
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Title: Journal of the American Chemical Society Volume: 133 ISSN: 1520-5126 ISO Abbreviation: J. Am. Chem. Soc. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-27 Completed Date: 2011-08-19 Revised Date: 2012-05-07 |
Medline Journal Info:
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Nlm Unique ID: 7503056 Medline TA: J Am Chem Soc Country: United States |
Other Details:
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Languages: eng Pagination: 6517-20 Citation Subset: IM |
Copyright Information:
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© 2011 American Chemical Society |
Affiliation:
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Department of Chemistry, Columbia University, New York, New York 10027, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aldehydes
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chemistry* Catalysis Silanes / chemistry* Stereoisomerism |
| Grant Support | |
ID/Acronym/Agency:
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R01 GM058133-11/GM/NIGMS NIH HHS; R01 GM058133-12/GM/NIGMS NIH HHS; R01 GM58133/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Aldehydes; 0/Silanes; 0/crotylsilane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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