Document Detail

Morbidity risk of schizophrenia to parents and siblings of schizophrenic patients.
MedLine Citation:
PMID:  3626197     Owner:  NLM     Status:  MEDLINE    
In order to estimate the familial morbidity risk of schizophrenia, parents and siblings of 1,691 inpatients meeting the DSM-III criteria for schizophrenia were investigated on the basis of a review of medical records, family history data and/or personal interviews. The morbidity risks of schizophrenia to parents and siblings of the schizophrenic probands were 4.0% and 4.1%, respectively, which were greater than the morbidity risk in the general population. Siblings of 118 probands whose parents suffered from schizophrenia were at a significantly greater risk of schizophrenia than siblings of 1,493 probands whose parents did not have schizophrenic illness. These findings support the notion of familial transmission of schizophrenia. A total of 16.4% of the schizophrenic probands had at least one first-degree relative with schizophrenia. This is significantly greater in the female probands than in the male probands.
A Shimizu; M Kurachi; N Yamaguchi; H Torii; K Isaki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Japanese journal of psychiatry and neurology     Volume:  41     ISSN:  0912-2036     ISO Abbreviation:  Jpn. J. Psychiatry Neurol.     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-09-25     Completed Date:  1987-09-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8610886     Medline TA:  Jpn J Psychiatry Neurol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  65-70     Citation Subset:  IM    
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MeSH Terms
Manuals as Topic
Middle Aged
Schizophrenia / diagnosis,  genetics*

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