| Morbidity and mortality due to ascariasis: re-estimation and sensitivity analysis of global numbers at risk. | |
| | |
MedLine Citation:
|
PMID: 9236818 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This paper presents estimates of the global numbers of people at risk from morbidity related to infection with Ascaris lumbricoides and the numbers of deaths from this infection. Morbidity is classified into 4 types: deficits in growth and fitness which are contemporaneous with infection, or permanent, overt acute illness of mild to moderate severity, and complications involving hospitalization. The estimation of morbidity is based on theoretical models of parasite distributions developed in previous papers. A sensitivity analysis is carried out in which parameters of the model are varied using a Latin hypercube sampling technique. The results estimate approximately 1300 million infections globally with 59 million at risk of some morbidity. The estimate for acute illness is 12 million cases per year with approximately 10,000 deaths. Most morbidity is in children. Sensitivity analysis suggests that infection estimates will not vary greatly with changes in parameter values but that morbidity estimates may be highly variable. |
| | |
Authors:
|
N R de Silva; M S Chan; D A Bundy |
Related Documents
:
|
19590898 - Determinants and consequences of interspecific body size variation in tetraphyllidean t... 18686238 - Bayesian modelling of geostatistical malaria risk data. 2124438 - The prevalence of trypanosoma cruzi and the demography of dog populations after insecti... 19967508 - Host resistance assays including bacterial challenge models. 21562828 - Protein-protein docking on molecular models of aspergillus niger rnase and human actin:... 15688568 - Spacetime stereo: a unifying framework for depth from triangulation. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Tropical medicine & international health : TM & IH Volume: 2 ISSN: 1360-2276 ISO Abbreviation: Trop. Med. Int. Health Publication Date: 1997 Jun |
Date Detail:
|
Created Date: 1997-08-08 Completed Date: 1997-08-08 Revised Date: 2010-08-25 |
Medline Journal Info:
|
Nlm Unique ID: 9610576 Medline TA: Trop Med Int Health Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 519-28 Citation Subset: IM |
Affiliation:
|
Wellcome Trust Centre for the Epidemiology of Infectious Disease, University of Oxford, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Animals Ascariasis / complications, epidemiology*, mortality Ascaris lumbricoides* Child Child, Preschool Humans Infant Models, Biological Morbidity Regression Analysis Sensitivity and Specificity |
| Grant Support | |
ID/Acronym/Agency:
|
//Wellcome Trust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Reproductive and socio-economic correlates of maternal haemoglobin levels in a rural area of Papua N...
Next Document: Gender and ethnic differences in onchocercal skin disease in Oyo State, Nigeria.