| Morbidity and mortality after RSV-associated hospitalizations among premature Canadian infants. | |
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MedLine Citation:
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PMID: 14615714 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the impact of respiratory syncytial virus (RSV) infections on subsequent health care resource utilization in preterm infants. STUDY DESIGN: Analysis of data from 2415 preterm infants (32 to 35 weeks gestational age [GA]) hospitalized for proven or probable RSV and matched to 20,254 control infants. RESULTS: Mean (SD) age at the index admission was 7.7 (5.5) months; 46% of the infants were male. Mean (SD) subsequent health services, excluding the index event, for the RSV cohort and control infants, respectively, were hospitalization, 2.96 (2.81) versus 1.28 (1.42); special care unit visits, 0.67 (1.70) versus 0.40 (0.33); respiratory therapy visits, 0:31 (0.70) versus 0.13 (0.37); physician consults, 3.61 (4.54) versus 0.89 (1.12); in-hospital procedures, 1.05 (4.02) versus 0.81 (1.51); outpatient visits, 18.4 (10.58) versus 7.54 (4.31); and mean (SD) inpatient days, 14.71 (18.69) versus 5.04 (7.09). All differences were statistically significant (P<.001). Diagnoses for the RSV and control cohorts were respiratory conditions (64% versus 13%), fever (2.7% versus 0.7%), anorexia (2.2% versus 0.6%), lack of normal physiological development (2.8% versus 1.1%; P<.05), overall deaths (8.1% versus 1.6%; P<.001), and sudden death (6.1% versus 0.3%; P<.001). CONCLUSIONS: RSV hospitalization in healthy premature infants is associated with a significant increase in subsequent health care resource utilization and mortality. Results support prophylaxis of premature infants against RSV hospitalization. |
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Authors:
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John S Sampalis |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of pediatrics Volume: 143 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-11-17 Completed Date: 2004-01-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: S150-6 Citation Subset: AIM; IM |
Affiliation:
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McGill University, University of Montreal, JSS Medical Research Inc, Montreal, Quebec, Canada. jsampali@jssresearch.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bronchiolitis
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mortality*,
rehabilitation*,
virology Canada / epidemiology Cohort Studies Female Gestational Age Hospitalization / statistics & numerical data Humans Infant Infant, Newborn Infant, Premature Infant, Premature, Diseases / rehabilitation*, virology Male Respiratory Syncytial Virus Infections / rehabilitation*, virology Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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