Document Detail


Morbidity of low-birthweight infants with intrauterine cocaine exposure.
MedLine Citation:
PMID:  8426379     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of intrauterine cocaine exposure on 158 low-birthweight infants (500 g to 2500 g) were compared with 536 low-birthweight infants not known to be exposed to cocaine who were admitted to our neonatal intensive care unit. Univariate analyses indicated that drug-exposed infants had lower birthweights when compared with control infants. Frequency of necrotizing enterocolitis differed between the drug-exposed infants and controls (11% versus 6%). Frequency of severe respiratory distress syndrome, severe intraventricular hemorrhage, and bronchopulmonary dysplasia did not differ between groups of similar birthweight. We conclude that the most evident risks of prenatal cocaine exposure are low birthweight and increased incidence of necrotizing enterocolitis.
Authors:
S Sehgal; C Ewing; P Waring; R Findlay; X Bean; H W Taeusch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  85     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-03-01     Completed Date:  1993-03-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  20-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Drew University College of Medicine, Los Angeles, California.
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MeSH Terms
Descriptor/Qualifier:
Cocaine / adverse effects*
Enterocolitis, Pseudomembranous / chemically induced
Female
Humans
Infant Mortality*
Infant, Low Birth Weight*
Infant, Newborn
Infant, Premature
Los Angeles / epidemiology
Maternal-Fetal Exchange*
Pregnancy
Prenatal Exposure Delayed Effects
Chemical
Reg. No./Substance:
50-36-2/Cocaine
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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